Detalhe da pesquisa
1.
Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.
J Pharmacol Exp Ther
; 365(3): 494-506, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29602831
2.
Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization.
J Pharmacol Exp Ther
; 354(2): 131-41, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26022002
3.
N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis.
Carcinogenesis
; 35(10): 2264-72, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25115443
4.
Single bioengineered ncRNA molecule for dual-targeting toward the control of non-small cell lung cancer patient-derived xenograft tumor growth.
Biochem Pharmacol
; 189: 114392, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359565
5.
In vivo fermentation production of humanized noncoding RNAs carrying payload miRNAs for targeted anticancer therapy.
Theranostics
; 11(10): 4858-4871, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33754032
6.
Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity.
Mol Ther Nucleic Acids
; 14: 498-508, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753993
7.
Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models.
Cancer Lett
; 442: 82-90, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389433
8.
Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models.
Oncotarget
; 8(19): 30742-30755, 2017 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28415566
9.
Genetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest.
Sci Rep
; 6: 26611, 2016 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27216562
10.
MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis.
Oncotarget
; 7(29): 45547-45561, 2016 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27322206
11.
Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth.
Biochem Pharmacol
; 98(4): 602-13, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26518752
12.
[Application of lateral cervical incision in the removal of the cervical esophageal foreign body].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
; 45(6): 486-90, 2010 Jun.
Artigo
em Zh
| MEDLINE | ID: mdl-21055327